# 一位患有特發性肺纖維化的個案正在開始服用 pirfenidone。請將每個陳述拖曳到適當的類別中。

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=522578&lang=zh-tw  
> language: zh-TW  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## 題目

一位患有特發性肺纖維化的個案正在開始服用 pirfenidone。請將每個陳述拖曳到適當的類別中。

**1.** 每劑處方藥物與食物一起服用

Select a category
Unsafe
Appropriate

**2.** 戶外穿戴防護衣物並使用廣效防曬乳

Select a category
Unsafe
Appropriate

**3.** 完成醫囑的肝功能檢查並報告深色尿液或黃疸

Select a category
Unsafe
Appropriate

**4.** 使用日曬床以建立對光敏感性的耐受性

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Unsafe
Appropriate

**5.** 恢復吸菸，因為它會增加 pirfenidone 的效力

Select a category
Unsafe
Appropriate

**6.** 忽略水泡性皮疹直到下次常規預約

Select a category
Unsafe
Appropriate

## 解析

Pirfenidone 應與食物一起服用，需要監測肝功能，並要求每天防曬。吸菸會降低藥物暴露，而嚴重皮疹或肝損傷症狀需要及時追蹤。

## 深入解析

快速解答
區分安全的抗纖維化自我管理與暴露和毒性風險。

為何這是正確的
食物可以減少噁心和頭暈，而防曬可以減少光敏感性。肝臟症狀和嚴重皮膚反應不是可以忽略的常規副作用。

簡單類比或心像
使用封閉式藥物安全循環：識別暴露、連結新發現、中斷進一步傷害、支持生理功能，並隨時間驗證反應。

記憶點
暴露、交互作用、毒性模式、立即行動、系列再評估。

NCLEX 決策規則
選擇能降低最直接藥物相關風險的行動，同時保留監測和升級處理。

為何其他選項是錯誤的
持續暴露、僅治療單一症狀或延遲再評估的選項會使毒性過程持續活躍。參考資料
1DailyMed: ESBRIET (pirfenidone)食物給藥、肝功能監測、光敏感性預防和吸菸導致的暴露減少

## 臨床情境

藥物安全審查
驗證適應症、途徑、交互作用藥物、目前的呼吸道和胃腸道發現、授權行動和可測量的後續追蹤。

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