# Which prescription is consistent with the labeled use of oral fosfomycin tromethamine?

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=516670&lang=en  
> language: en  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## Question

Which prescription is consistent with the labeled use of oral fosfomycin tromethamine?

## Option

1. One sachet dissolved in water for an adult woman with susceptible uncomplicated acute cystitis. **✔ Correct answer**
2. One dry sachet swallowed each morning for 7 days to treat fever, flank pain, and suspected pyelonephritis.
3. The oral granules administered through an IV infusion to treat a perinephric abscess and systemic urinary infection.
4. One sachet repeated every 6 hours as empiric treatment for a febrile upper urinary tract infection.

**Correct answer: 1**

## Explanation

Oral fosfomycin tromethamine is labeled as one dissolved sachet for uncomplicated acute cystitis in adult women due to susceptible organisms; it is not indicated for pyelonephritis or perinephric abscess.

## In-depth explanation

Quick answer
Match fosfomycin to uncomplicated lower urinary infection.

Why this is correct
The product is mixed with water and taken immediately as a single sachet. Fever, flank pain, or upper-tract infection requires a different evaluation and treatment plan.

Easy analogy or mental picture
A lower-tract key does not open the kidney-infection door.

Memory hook
Fosfomycin sachet: uncomplicated cystitis, not pyelonephritis.

NCLEX decision rule
Verify site, severity, susceptibility, formulation, preparation, and number of doses before administration.

Why the other choices are wrong
Dry ingestion, IV use, and repeated empiric dosing are not the labeled regimen described for this product.References
1DailyMed: Fosfomycin TromethamineSingle-sachet treatment of uncomplicated acute cystitis in women and nonindication for pyelonephritis

## Clinical scenario

Fosfomycin check
Confirm lower-tract symptoms, absence of systemic or flank findings, culture context, allergy, preparation in water, and single-dose teaching.

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