# 審查周邊神經阻斷後的趨勢，並確定併發症和優先應對措施。

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=515768&lang=zh-tw  
> language: zh-TW  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## 題目

審查周邊神經阻斷後的趨勢，並確定併發症和優先應對措施。

| Time | Data |
| --- | --- |
| 0 minutes | 布比卡因周邊神經阻斷完成；個案清醒；血壓 128/74 mm Hg；心率 82 次/分 |
| 3 minutes | 新出現口周麻木、金屬味、耳鳴和躁動 |
| 5 minutes | 全身性癲癇發作；血氧飽和度 86%；血壓 84/48 mm Hg |
| 7 minutes | 儘管有氧氣和氣道支持，仍出現寬 QRS 波群心室心律不整 |

Q1. 最可能的併發症是什麼？

局部麻醉劑全身毒性
預期的阻斷作用開始
孤立的血管迷走神經事件

Q2. 哪種治療途徑是優先事項？

再給予一次局部麻醉劑推注
啟動 LAST 清單並早期給予醫囑的 20% 脂肪乳劑
使用血管加壓素作為首選解毒劑

## 解析

從口周麻木和耳鳴進展到癲癇發作、低血壓和心室心律不整是局部麻醉劑全身毒性，需要氣道支持和早期 20% 脂肪乳劑治療。

## 深入解析

快速解答
辨識局部麻醉劑全身毒性 (LAST) 並啟動脂肪乳劑搶救途徑。

為何這是正確的
全身性局部麻醉劑暴露後，神經學症狀可能先於心血管衰竭。ASRA 清單優先考慮尋求協助、氣道和癲癇管理，以及早期 20% 脂肪乳劑，並採取 LAST 特定的復甦預防措施。

簡單類比或心像
警告聲變成電風暴；在病情惡化前，伸手拿取 LAST 搶救包。

記憶點
口麻、耳鳴、癲癇、心律不整：考慮 LAST 和脂肪乳劑。

NCLEX 決策規則
將神經學和心血管線索視為一個不斷演變的毒性症候群來追蹤。

為何其他選項是錯誤的
標準大劑量腎上腺素、血管加壓素、β 受體阻斷劑、鈣通道阻斷劑和更多的局部麻醉劑在清單中明確是不安全的選擇。References
1ASRA LAST ChecklistEarly 20% lipid emulsion, altered resuscitation, monitoring, and avoidance list

## 臨床情境

LAST 搶救
停止局部麻醉劑、呼叫協助、支持氣道、適當治療癲癇，並啟動醫囑的 20% 脂肪乳劑方案。

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