# 一位 70 公斤的個案，在達普頌暴露後出現有症狀的後天性變性血紅素血症，其經授權的亞甲藍劑量為 1 mg/kg 靜脈注射。藥瓶含有 5 mg/mL。完成計算。 > source: MyMerci (mymerci.kr) > url: https://mymerci.kr/pages/nclex_q.php?qn_id=515767&lang=zh-tw > language: zh-TW > subject: Adverse Effects/Contraindications/Interactions > category: PPT ## 題目 一位 70 公斤的個案，在達普頌暴露後出現有症狀的後天性變性血紅素血症，其經授權的亞甲藍劑量為 1 mg/kg 靜脈注射。藥瓶含有 5 mg/mL。完成計算。 計算出的劑量是 ::선택::7 毫克35 毫克70 毫克350 毫克。濃度為 5 mg/mL 時，護理師應準備 ::선택::1.4 毫升7 毫升14 毫升70 毫升。給藥前，請確認 ::선택::G6PD 和血清素能藥物風險僅口溫氯化鈉是所需的稀釋劑脈搏血氧飽和度為 100%。 ## 解析 劑量為 70 毫克，體積為 14 毫升。給藥前，護理師必須確認 G6PD 和血清素能藥物風險以及靜脈注射通路暢通。 ## 深入解析 快速解答 在安全篩查後，準備70 毫克，即 14 毫升。 為何這是正確的 70 公斤的個案，每公斤 1 毫克等於 70 毫克。濃度為 5 mg/mL 時，70 毫克除以 5 mg/mL 等於 14 毫升。亞甲藍在 G6PD 缺乏症患者中可能引起溶血，並與血清素能藥物和鴉片類藥物一起使用時可能導致嚴重的血清素毒性。 簡單類比或心像 計算解毒劑，然後檢查兩扇上鎖的門：G6PD 和血清素能藥物暴露。 記憶點 1 mg/kg；將毫克數除以 5 mg/mL。 NCLEX 決策規則 計算準確性不能取代禁忌症和交互作用篩查。 為何其他選項是錯誤的 單獨的脈搏血氧飽和度在變性血紅素血症中可能具有誤導性，且未經重新評估不應給予經驗性重複劑量。References 1DailyMed: Dapsone GelMethemoglobinemia warning and cyanosis recognition 2DailyMed: Methylene Blue Injection1 mg/kg dose, 5 mg/mL concentration, G6PD and serotonergic safety warnings ## 臨床情境 變性血紅素血症解毒劑檢查 確認暴露、血氧協同測量、症狀、G6PD 狀態、血清素能藥物、腎功能、劑量、濃度和靜脈通路。 ## 相同主題題目 - [A client is admitted to the emergency department after ingesting an unknown amount of acet…](https://mymerci.kr/pages/nclex_q.php?qn_id=362720&lang=zh-tw) - [A client with chronic heart failure is prescribed metoprolol 25 mg orally twice daily. Bef…](https://mymerci.kr/pages/nclex_q.php?qn_id=362756&lang=zh-tw) - [A 28-year-old client with type 1 diabetes receives regular insulin 6 units and NPH insulin…](https://mymerci.kr/pages/nclex_q.php?qn_id=362792&lang=zh-tw) - [A client receives IV vancomycin 1 g every 12 hours for MRSA bacteremia. Before the next do…](https://mymerci.kr/pages/nclex_q.php?qn_id=362833&lang=zh-tw) - [A client with bipolar disorder has been taking lithium carbonate 600 mg orally three times…](https://mymerci.kr/pages/nclex_q.php?qn_id=362894&lang=zh-tw) - [A nurse is monitoring a client receiving a continuous IV heparin infusion for pulmonary em…](https://mymerci.kr/pages/nclex_q.php?qn_id=363988&lang=zh-tw) - [A nurse is preparing to initiate a weight-based continuous IV unfractionated heparin infus…](https://mymerci.kr/pages/nclex_q.php?qn_id=364107&lang=zh-tw) - [A nurse is providing discharge teaching to a 65-year-old client newly prescribed warfarin …](https://mymerci.kr/pages/nclex_q.php?qn_id=364872&lang=zh-tw) ## 以其他語言閱讀 - [en](https://mymerci.kr/pages/nclex_q.php?qn_id=515767&lang=en) - [ko](https://mymerci.kr/pages/nclex_q.php?qn_id=515767&lang=ko) - [ja](https://mymerci.kr/pages/nclex_q.php?qn_id=515767&lang=ja) - [zh-TW](https://mymerci.kr/pages/nclex_q.php?qn_id=515767&lang=zh-tw) - [vi](https://mymerci.kr/pages/nclex_q.php?qn_id=515767&lang=vi) --- More free questions: [NCLEX-RN 題庫](https://mymerci.kr/pages/nclex_bank.php?lang=zh-tw) _僅供學習參考。實際臨床請遵循最新指引與所屬機構規範。_