# 一位患有胰外分泌功能不全的病人在用餐和點心時服用胰脂肪酶。下列哪一項發現最能顯示藥物有效？

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=498893&lang=zh-tw  
> language: zh-TW  
> subject: Adverse Effects/Contraindications/Interactions  
> category: ROR

## 題目

一位患有胰外分泌功能不全的病人在用餐和點心時服用胰脂肪酶。下列哪一項發現最能顯示藥物有效？

## 選項

1. 空腹血糖下降，且口渴頻率減少
2. 油膩糞便減少，且病人體重開始穩定 **✔ 正確答案**
3. 血清脂肪酶升高，且腹部壓痛加劇
4. 尿量增加，且依賴性水腫減輕

**正確答案: 2**

## 解析

胰脂肪酶補充消化酵素，使脂肪、蛋白質和碳水化合物能更有效地被吸收。油膩糞便減少和體重穩定顯示，在伴隨食物服用時，消化和營養吸收獲得改善。

## 深入解析

快速解答
脂肪瀉減少且體重穩定，顯示胰酵素替代療法有效。

為什麼這是正確的
缺乏足夠的胰酵素時，飲食中的脂肪無法被充分消化，會產生大量油膩糞便和體重減輕。隨餐服用胰脂肪酶可改善營養分解，因此糞便品質和營養狀態是實用的反應指標。

簡單比喻或心智圖像
胰脂肪酶為消化工廠提供缺少的工具，使食物能被分解吸收。這個比喻說明了替代療法，但並不表示藥物能恢復胰臟組織或治療所有疼痛原因。

記憶掛鉤
胰酵素有效運作意味著較少的油膩和較穩定的體重。

NCLEX 決策規則
透過改善的消化和營養來評估酵素替代療法。觀察脂肪瀉減少、體重趨勢改善和較少的吸收不良症狀，而非不相關的血糖、腎臟或水腫變化。

為什麼其他選項是錯的
胰脂肪酶並非用於降低血糖或增加尿量。脂肪酶升高和壓痛加劇暗示持續的胰臟發炎，而非治療成功。參考文獻

- [1]NCSBN: 2026 NCLEX-RN Test PlanNational Council of State Boards of Nursing

- [2]DailyMed: Creon Pancrelipase Prescribing InformationU.S. National Library of Medicine, updated July 2026

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