# 一位中樞性尿崩症個案接受desmopressin治療。哪項發現最能顯示對治療的預期反應？

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=498730&lang=zh-tw  
> language: zh-TW  
> subject: Postsurgical Complications  
> category: ROR

## 題目

一位中樞性尿崩症個案接受desmopressin治療。哪項發現最能顯示對治療的預期反應？

## 選項

1. 尿量為 360 mL/hr，且尿液比重為 1.001
2. 尿量為 200 mL/hr，且血清鈉為 153 mEq/L
3. 尿量為 75 mL/hr，且尿液比重為 1.015 **✔ 正確答案**
4. 尿量為 25 mL/hr，且血清鈉為 128 mEq/L 伴隨頭痛

**正確答案: 3**

## 解析

Desmopressin取代抗利尿活性，因此有效的治療會減少過多的尿量並產生較濃縮的尿液。極低的尿量伴隨低血鈉及頭痛，暗示水分滯留過多，而非預期的平衡反應。

## 深入解析

快速解答
較低且足夠的尿量，伴隨尿液濃縮度增加，顯示預期的抗利尿反應。

為什麼這是正確的
中樞性尿崩症因抗利尿激素活性缺乏，導致大量稀釋尿液。Desmopressin應減少尿量並增加尿液滲透壓或比重，同時維持安全的體液及鈉平衡。

簡單比喻或心智圖像
Desmopressin部分關閉了一個讓過多稀釋水分流失的排水口。期望的結果是控制流量，而非堵塞排水口，且此比喻不能取代鈉及神經學監測。

記憶掛鉤
有效的desmopressin使尿液不過量且更濃縮，而不會發生水中毒。

NCLEX 決策規則
評估抗利尿替代治療時，應將尿量與尿液濃縮度及鈉狀態配對。持續稀釋性多尿表示效果不足，而寡尿伴隨低血鈉症狀則暗示效果過度。

為什麼其他選項是錯的
大量稀釋尿液顯示持續性尿崩症。持續高血鈉伴隨多尿是反應不足，而極低尿量伴隨低血鈉及頭痛則表示水分中毒。參考文獻

- [1]NCSBN: 2026 NCLEX-RN Test PlanNational Council of State Boards of Nursing

- [2]DailyMed: Desmopressin Acetate Oral SolutionU.S. National Library of Medicine

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