# 一名58歲高血壓個案詢問護理師，感冒鼻塞可否服用pseudoephedrine 60 mg。最適當的回答為何？

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=391791&lang=zh-tw  
> language: zh-TW  
> subject: Medical Emergencies  
> category: PA

## 題目

一名58歲高血壓個案詢問護理師，感冒鼻塞可否服用pseudoephedrine 60 mg。最適當的回答為何？

## 選項

1. 可依需要以任何劑量長期服用pseudoephedrine。
2. Pseudoephedrine是交感神經刺激藥，可能升高血壓與心跳；應避免，並考慮生理食鹽水鼻噴劑或鼻用類固醇。 **✔ 正確答案**
3. Pseudoephedrine不會影響血壓。
4. 服用pseudoephedrine期間停止lisinopril。

**正確答案: 2**

## 解析

正確 (2)：Pseudoephedrine是α腎上腺素致效的交感神經刺激藥，會升高血壓與心跳。高血壓、冠心病、甲狀腺機能亢進者應避免。較安全替代包括生理食鹽水鼻噴劑或沖洗、鼻用類固醇（fluticasone、mometasone），或短期局部鼻充血解除劑。(1) 錯誤。(3) 劑量越高心血管風險越大。(4) 停用降壓藥會使血壓惡化。

## 深入解析

記憶提示 Pseudoephedrine =「Pseudo-EPI」：交感神經刺激會升血壓。未控制高血壓、冠心病、甲狀腺機能亢進、近期MAOI使用禁忌。因可作為methamphetamine前驅物，需櫃台管制。

## 臨床情境

情境 58歲男性，高血壓以lisinopril控制，詢問是否可因感冒鼻塞服用pseudoephedrine 60 mg PO q6h。

## 重要概念

- **交感神經刺激性鼻充血解除劑** — 造成鼻黏膜血管收縮的α致效劑；pseudoephedrine、phenylephrine。
- **心血管禁忌** — 未控制高血壓、冠心病、近期心肌梗塞、甲狀腺機能亢進、MAOI使用。
- **較安全替代方案** — 生理食鹽水噴劑、鼻用類固醇、鼻用抗組織胺，較適合高血壓者。

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