# 一名因重度氣喘使用高劑量吸入fluticasone 1000 mcg/日加每日prednisone 7.5 mg的病人，在類流感疾病後出現發燒、嘔吐與低血壓。優先護理行動是什麼？

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=391774&lang=zh-tw  
> language: zh-TW  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## 題目

一名因重度氣喘使用高劑量吸入fluticasone 1000 mcg/日加每日prednisone 7.5 mg的病人，在類流感疾病後出現發燒、嘔吐與低血壓。優先護理行動是什麼？

## 選項

1. 給予IV補鉀
2. 預期給予IV hydrocortisone、IV normal saline與dextrose，因疑似腎上腺危象 **✔ 正確答案**
3. 暫停所有氣喘藥並4小時後重新評估
4. 鼓勵口服水分，30分鐘後再測血壓

**正確答案: 2**

## 解析

正解 (2): 長期高劑量ICS加慢性全身性類固醇會造成HPA軸抑制；急性壓力如疾病、嘔吐、手術時若無stress-dose steroid，會誘發腎上腺危象，出現低血壓、低血糖、低鈉、高鉀、虛弱。治療為IV hydrocortisone 100 mg STAT、含dextrose的IV saline與支持治療。(1) 延誤可致命。(3) 腎上腺危象常低Na/高K，補K會惡化。(4) 不足。

## 深入解析

Memory Tip 長期類固醇 + 急性壓力 = Stress dose or Crash。發燒、手術、疾病時需依sick-day rules。CPG 慢性類固醇使用者應配戴MedicAlert並攜帶緊急hydrocortisone。

## 臨床情境

Scenario 48歲女性，因重度氣喘使用高劑量ICS + prednisone 7.5 mg/日 2年。出現發燒、嘔吐、BP 86/52、虛弱、混亂、指尖血糖62。

## 重要概念

- **腎上腺危象** — 急性glucocorticoid不足造成休克、低血糖與電解質異常；需緊急hydrocortisone。
- **HPA軸抑制** — 長期外源性類固醇造成下視丘-腦下垂體-腎上腺軸抑制。
- **Sick-day rules** — 疾病、手術或創傷時增加類固醇壓力劑量以預防危象。

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