# 一位患有難治型思覺失調症的個案正要開始使用clozapine。在每次給藥前，必須記錄哪一項基礎實驗室檢驗？

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=391727&lang=zh-tw  
> language: zh-TW  
> subject: Medical Emergencies  
> category: PA

## 題目

一位患有難治型思覺失調症的個案正要開始使用clozapine。在每次給藥前，必須記錄哪一項基礎實驗室檢驗？

## 選項

1. 血紅素A1c
2. 絕對嗜中性白血球數（ANC） **✔ 正確答案**
3. 肝酵素
4. 血清鈉

**正確答案: 2**

## 解析

正確答案 (2)：Clozapine 帶有嚴重顆粒性白血球缺乏症（約1%發生率）的加框警語。Clozapine REMS 計畫要求在每次給藥前須有文件記錄 ANC ≥1500/mm³——前6個月每週一次，第7至12個月每兩週一次，之後每月一次。若 ANC

## 深入解析

Memory Tip: Clozapine = ANC clock.

## 臨床情境

Scenario 28-year-old male with treatment-resistant schizophrenia starting clozapine 12.5 mg PO BID.

## 重要概念

- **Clozapine REMS** — Restricted-distribution program requiring documented ANC monitoring.
- **Agranulocytosis** — Severe neutropenia increasing fatal infection risk.
- **Treatment-resistant schizophrenia** — Schizophrenia failing adequate trials of at least two other antipsychotics.

## 相同主題題目

- [A nurse is caring for an alert adult client with type 1 diabetes who reports tremors, swea…](https://mymerci.kr/pages/nclex_q.php?qn_id=360524&lang=zh-tw)
- [A 68-year-old client with COPD is admitted with shortness of breath and SpO2 86% on room a…](https://mymerci.kr/pages/nclex_q.php?qn_id=362940&lang=zh-tw)
- [A 58-year-old client arrives at the emergency department with crushing substernal chest pa…](https://mymerci.kr/pages/nclex_q.php?qn_id=362976&lang=zh-tw)
- [A 72-year-old client is brought to the emergency department by family who report that the …](https://mymerci.kr/pages/nclex_q.php?qn_id=363003&lang=zh-tw)
- [A 79-year-old client is admitted from a long-term care facility with diarrhea, decreased o…](https://mymerci.kr/pages/nclex_q.php?qn_id=363089&lang=zh-tw)
- [A 76-year-old female with chronic heart failure and atrial fibrillation receives digoxin 0…](https://mymerci.kr/pages/nclex_q.php?qn_id=374883&lang=zh-tw)
- [A 70-year-old client on long-term digoxin therapy reports new yellow-green halos around li…](https://mymerci.kr/pages/nclex_q.php?qn_id=374884&lang=zh-tw)
- [A 58-year-old client with type 2 diabetes mellitus and migraine prophylaxis is taking prop…](https://mymerci.kr/pages/nclex_q.php?qn_id=374893&lang=zh-tw)

## 以其他語言閱讀

- [en](https://mymerci.kr/pages/nclex_q.php?qn_id=391727&lang=en)
- [ko](https://mymerci.kr/pages/nclex_q.php?qn_id=391727&lang=ko)
- [ja](https://mymerci.kr/pages/nclex_q.php?qn_id=391727&lang=ja)
- [zh-TW](https://mymerci.kr/pages/nclex_q.php?qn_id=391727&lang=zh-tw)
- [vi](https://mymerci.kr/pages/nclex_q.php?qn_id=391727&lang=vi)

---

More free questions: [NCLEX-RN 題庫](https://mymerci.kr/pages/nclex_bank.php?lang=zh-tw)

_僅供學習參考。實際臨床請遵循最新指引與所屬機構規範。_