# A client with severe TBI on ICP monitor develops new BP 198/56, HR 42, and irregular respirations. Which actions should the nurse anticipate? Select all that apply.

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=375148&lang=en  
> language: en  
> subject: Pharmacological and Parenteral Therapies  
> category: PPT

## Question

A client with severe TBI on ICP monitor develops new BP 198/56, HR 42, and irregular respirations. Which actions should the nurse anticipate? Select all that apply.

1

Recognize Cushing triad as a sign of impending herniation and notify provider stat

2

Prepare for emergent neurosurgical decompression (craniectomy or hematoma evacuation)

3

Administer hyperosmolar therapy: hypertonic saline (3 percent or 23.4 percent bolus) or mannitol

4

Briefly hyperventilate to PaCO2 30-35 as bridge to definitive decompression

5

Place the client in a supine position with the head flat to promote cerebral perfusion.

## Explanation

Cushing triad (HTN, bradycardia, irregular respirations) plus anisocoria signals impending or active herniation in TBI — emergent action: hyperosmolar therapy (3 percent NaCl bolus 250 mL or 23.4 percent 30 mL or mannitol 1 g/kg), brief hyperventilation to PaCO2 30-35 as a BRIDGE only (sustained low PaCO2 worsens ischemia), and emergent neurosurgical decompression. HOB FLAT worsens ICP — keep at 30 degrees with neutral neck. CSF drainage if EVD present.

## In-depth explanation

ICP target under 22 mmHg. CPP target 60-70. After herniation event: continue tier-2 therapies (cooling, barbiturate, paralytics) per neurosurgical guidance.

## Clinical scenario

Pupil now sluggish and 5 mm on the right. ICP 28 mmHg sustained.

## Key concepts

- **Cushing triad** — Hypertension, bradycardia, irregular respirations from severely elevated ICP.
- **hyperosmolar therapy** — Hypertonic saline or mannitol drawing water from brain tissue.
- **cerebral herniation** — Brain displacement past dural folds; emergent decompression required.

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