# A client with GBS reports increasing weakness with bedside vital capacity (VC) dropping from 22 to 14 mL/kg over 4 hours. Which interventions should the nurse anticipate? Select all that apply.

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=375096&lang=en  
> language: en  
> subject: Management of Care  
> category: MOC

## Question

A client with GBS reports increasing weakness with bedside vital capacity (VC) dropping from 22 to 14 mL/kg over 4 hours. Which interventions should the nurse anticipate? Select all that apply.

1

Implement DVT prophylaxis with mechanical and pharmacologic measures

2

Monitor for autonomic dysfunction with continuous BP and cardiac monitoring

3

Prepare for elective intubation before respiratory failure becomes emergent

4

Initiate IVIG or plasmapheresis as ordered

5

Use noninvasive ventilation as the definitive airway because of bulbar weakness

## Explanation

Impending neuromuscular respiratory failure in GBS: VC under 15-20 mL/kg, NIF less negative than -25 to -30 cm H2O, single breath count under 20, weakening cough or bulbar dysfunction. ELECTIVE intubation prevents emergent crash airway with aspiration. IVIG (0.4 g/kg/day × 5 days) or plasmapheresis are equivalent disease-modifying therapies; STEROIDS do NOT help. NIV is generally avoided in GBS with bulbar weakness because of aspiration risk and progressive failure — definitive intubation preferred. Autonomic dysautonomia (BP swings, dysrhythmia, ileus) requires continuous monitoring. DVT prophylaxis (SCDs plus heparin) is essential because of immobility.

## In-depth explanation

Memorize 20/30/40: VC under 20, NIF less negative than -30, MIP not adequate, indicates intubation. Weakening single breath count is rapid bedside trend.

## Clinical scenario

NIF -22 cm H2O. Single breath count 12. SpO2 95 percent on room air. Bulbar weakness with weak cough.

## Key concepts

- **vital capacity** — Maximum exhaled volume after deepest inhalation; declines in neuromuscular failure.
- **IVIG** — Intravenous immunoglobulin; first-line GBS therapy alongside plasmapheresis.
- **dysautonomia** — Autonomic instability with BP swings, arrhythmias, GI changes; high mortality in GBS if missed.

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