# A nurse is teaching a patient discharged on oral potassium chloride (extended-release tablet) 20 mEq twice daily for diuretic-induced hypokalemia. Which teaching points should be included? Select all that apply.

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> language: en  
> subject: Pharmacological and Parenteral Therapies  
> category: PPT

## Question

A nurse is teaching a patient discharged on oral potassium chloride (extended-release tablet) 20 mEq twice daily for diuretic-induced hypokalemia. Which teaching points should be included? Select all that apply.

1

Take the tablets WITH FOOD or a full glass of water (8 oz, 240 mL) to reduce GI irritation and esophageal/gastric ulceration risk.

2

Do NOT crush, chew, or split the extended-release tablets — destroying the matrix releases all the potassium at once and causes severe GI injury.

3

Report symptoms of hyperkalemia — muscle weakness, palpitations, GI cramps, or paresthesias — to the provider immediately.

4

Avoid potassium-containing salt substitutes (such as Morton Lite Salt) and excessive potassium-rich foods because they can cause hyperkalemia when combined with KCl.

5

If you forget a dose, taking both doses at the next scheduled interval is acceptable because the extended-release formulation prevents a potassium spike.

## Explanation

Oral KCl teaching: take with food and full glass of water (GI protection), NEVER crush or split extended-release (causes esophageal/gastric ulcer), avoid K+ salt substitutes (hyperkalemia), report hyperkalemia symptoms. Choice 5 is dangerous — double-dosing potassium can cause life-threatening hyperkalemia; the rule is take a missed dose if remembered soon, or skip and take the next scheduled dose at usual time, but never double up.

## In-depth explanation

The "never crush" rule for KCl extended-release is among the most-tested NCLEX medication-administration points. Crushing destroys the extended-release matrix, dumping all the potassium at once and causing severe esophageal/gastric ulceration. Other never-crush drugs: nitroglycerin SR, aspirin EC, omeprazole DR, levodopa CR. Salt substitutes are a high-yield trap because patients/families often consider them "healthy".

## Clinical scenario

Patient on chronic **furosemide and oral KCl extended-release 20 mEq BID** for diuretic-induced hypokalemia. Discharge teaching needed.

## Key concepts

- **Extended-release KCl** — Slow-release oral potassium; never crush/chew/split; take with food and water for GI protection.
- **Potassium salt substitutes** — Products like Morton Lite Salt contain potassium chloride; combined with KCl supplement can cause hyperkalemia.
- **Missed dose rule** — Take when remembered if soon; skip if close to next dose; NEVER double up — applies to KCl, anticoagulants, antihypertensives.

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