# 長期使用phenytoin之癲癇病人主訴新出現複視與步態不穩。Phenytoin濃度28 mcg/mL(治療10-20)。最適當之護理行動為何？

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=373129&lang=zh-tw  
> language: zh-TW  
> subject: NCLEX-RN  
> category: PPT

## 題目

長期使用phenytoin之癲癇病人主訴新出現複視與步態不穩。Phenytoin濃度28 mcg/mL(治療10-20)。最適當之護理行動為何？

## 選項

1. 維持現劑量；症狀與phenytoin無關。
2. 暫停下一劑並通報醫師，將病人列入跌倒預防，評估眼震與共濟失調。 **✔ 正確答案**
3. 將下一劑加倍以更快將濃度回到治療範圍。
4. 立即給予活性碳以吸附過量藥物。

**正確答案: 2**

## 解析

Phenytoin治療範圍10-20 mcg/mL。28為中毒。經典中毒表現：眼震(最早期徵象)、複視、共濟失調、口齒不清、意識混亂。行動：暫停劑量、通報醫師調整劑量、加入跌倒預防、完成神經學評估。劑量加倍(3)危險；活性碳(4)不適合慢性中毒(用於攝入~1小時內之急性過量)。

## 深入解析

Phenytoin濃度與徵象常考：10-20治療、20-30眼震+複視+共濟失調、30-40嗜睡、>40昏迷/發作(矛盾性)。最早可偵測之徵象為水平側視時眼震 — 應例行評估。

## 臨床情境

**長期使用phenytoin病人**主訴**新出現複視與步態不穩**。Phenytoin濃度**28 mcg/mL**(治療10-20)。生命徵象穩定，無活動性發作。

## 重要概念

- **Phenytoin治療濃度** — 10-20 mcg/mL；治療指數狹窄需例行TDM與中毒評估。
- **Phenytoin中毒進程** — 20-30眼震/複視/共濟失調、30-40嗜睡、>40昏迷或矛盾性發作。
- **例行眼震評估** — 慢性phenytoin病人每班檢查水平側視 — 最早期中毒徵象。

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