# A nurse cares for a client newly admitted with a positive surveillance culture for vancomycin-resistant enterococcus (VRE) of the rectum. Which infection prevention measures should the nurse implement? Select all that apply.

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=366709&lang=en  
> language: en  
> subject: Standard/Transmission-Based Precautions/Surgical Asepsis  
> category: SIPC

## Question

A nurse cares for a client newly admitted with a positive surveillance culture for vancomycin-resistant enterococcus (VRE) of the rectum. Which infection prevention measures should the nurse implement? Select all that apply.

1

Place the client in a negative-pressure airborne isolation room

2

Place the client on contact precautions in a private room or cohort with another VRE client

3

Allow the client to leave the room freely for ambulation in the hallway

4

Wear gown and gloves before every entry into the room

5

Dedicate equipment (BP cuff, stethoscope, thermometer) to this client

## Explanation

VRE is a multidrug-resistant organism (MDRO) transmitted by direct or indirect contact. CDC contact precautions: private room or cohort, gown and gloves on entry, dedicated equipment. Free ambulation in hallway is contraindicated for active MDRO precautions; the client may ambulate within the room or with cohort-specific protocols. Negative-pressure airborne isolation is for true airborne pathogens (TB, measles, varicella) — VRE is contact, not airborne.

## In-depth explanation

Clinical Judgment
VRE is contact-transmitted MDRO: private room or cohort, gown and gloves on entry, dedicated equipment. Hand hygiene with alcohol-based sanitizer or soap and water is acceptable (unlike C. diff which requires soap and water only). Surface disinfection with EPA-registered hospital-grade disinfectant.

Memory Tip
VRE: Contact + Gown/Gloves + Dedicated equipment. Alcohol OK (unlike C. diff)

KR vs U
CDC and Korean Society for Healthcare-Associated Infection Control share the same VRE protocol. Both jurisdictions report VRE bloodstream infections to surveillance systems and use active surveillance cultures in high-risk units (ICU, transplant).

## Clinical scenario

Clinical Practice Guide
CDC contact precautions for MDROs (MRSA, VRE, CRE):
- Private room or cohort with same MDRO
- Gown and gloves for every room entry
- Dedicated equipment; if shared, disinfect between clients with EPA-registered product
- Hand hygiene: alcohol-based sanitizer or soap and water (alcohol effective for MRSA/VRE/CRE; soap and water mandatory only for C. diff and norovirus due to spores)
- Environmental cleaning: high-touch surfaces with EPA-registered hospital disinfectant
- Active surveillance in high-risk units (ICU, transplant, dialysis)
- Discontinue per facility protocol with negative cultures (typically 2-3 negative)

Caution
VRE bloodstream infections in immunocompromised clients carry mortality up to 40 percent. Linezolid or daptomycin are typical first-line treatments; consult ID specialist. Hand hygiene compliance audit is the single most effective MDRO control intervention.

## Key concepts

- **VRE** — Vancomycin-resistant enterococcus, MDRO. Most often E. faecium or E. faecalis. Colonizes GI tract and skin; bloodstream infection in immunocompromised clients. Contact precautions, dedicated equipment, hand hygiene with alcohol or soap and water.
- **MDRO** — Multidrug-resistant organism. Includes MRSA, VRE, ESBL-producing organisms, CRE, MDR Pseudomonas/Acinetobacter, MDR-TB. CDC and Korean infection control require contact precautions; some require enhanced precautions per facility policy.
- **Active surveillance culture** — Routine screening of asymptomatic high-risk clients (ICU admission, transplant, recent hospitalization) for MDROs. Positive screen triggers contact precautions, decolonization protocols, and isolation. Reduces transmission and bloodstream infection rates.

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