# The patient's pulse exhibits a characteristic ______ amplitude after a premature beat, indicating post-extrasystolic potentiation.

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> url: https://mymerci.kr/pages/nclex_q.php?qn_id=168423  
> language: ko  
> subject: Diseases of the circulatory system

## 문제

The patient's pulse exhibits a characteristic ______ amplitude after a premature beat, indicating post-extrasystolic potentiation.

## 보기

1. increased **✔ 정답**
2. decreased
3. variable
4. normal
5. reduced

**정답: 1**

## 해설

Increased pulse amplitude following a premature beat is known as post-extrasystolic potentiation. This occurs because the longer compensatory pause allows more time for ventricular filling, resulting in a stronger subsequent contraction.

## 임상 시나리오

Post-Extrasystolic Potentiation (PESP):
- Definition: Enhanced cardiac contractility following premature ventricular contractions
- Mechanism: Increased calcium loading during compensatory pause
- Features:
* Longer diastolic filling time
* Enhanced ventricular contractility
* Stronger subsequent beat
* Increased stroke volume
* Higher pulse pressure

Clinical Significance:
- Diagnostic marker for heart failure
- Assessment of contractile reserve
- Indicator of myocardial viability
- Used in stress testing evaluation

Hemodynamic Changes:
- Increased systolic pressure
- Enhanced cardiac output
- Improved ventricular performance
- Augmented coronary blood flow
- Elevated ejection fraction

Related Phenomena:
- Force-frequency relationship
- Frank-Starling mechanism
- Calcium-dependent inotropy
- Mechanical restitution
- Contractile protein interaction

## 핵심 개념

- **increased** — To become greater in size, amount, or degree, showing enhancement or amplification
- **decreased** — To become smaller, fewer, or less in size, amount, or degree
- **variable** — Able to change or vary; not consistent or having a fixed pattern
- **normal** — Conforming to a standard; usual, typical, or expected
- **reduced** — Made smaller or less in size, amount, or degree; diminished

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