Applying the mhGAP-IG epilepsy criteria
The World Health Organization’s Mental Health Gap Action Programme Intervention Guide (mhGAP-IG) is designed for non-specialist health workers, including nurses, to identify and manage priority conditions such as epilepsy in primary care and community settings
Key point! Under mhGAP-IG, epilepsy is considered likely when there have been at least two seizures on two different days within the past year. The timing of the episodes, not simply the total number, determines whether the threshold for starting maintenance antiepileptic medicine has been reached.
For this 9-year-old boy, the first episode occurred
14 months ago, which places it outside the
12-month window. Episodes 2 and 3 both occurred
2 weeks ago, but they happened on the
same day—one in the morning and one in the afternoon. Because the mhGAP-IG rule requires seizures on
two different days, these two same-day episodes count as only one qualifying event within the past year. Therefore, the criterion of “at least two seizures on two different days in the past year” is not met, and the appropriate plan is to review the child again in
3 months to reassess for possible epilepsy.
Watch out! Other clinical definitions, such as “two unprovoked seizures more than
24 hours apart,” would count episodes 2 and 3 differently and might lead to starting treatment. However, the question stem specifically fixes the mhGAP-IG rule, which uses “two different days” rather than a strict 24-hour separation. This distinction is a common source of confusion in licensure exams.
The mhGAP-IG was developed precisely because non-specialist providers in under-resourced settings need a clear, practical algorithm for deciding when to initiate treatment. Studies evaluating mhGAP-based training for primary healthcare providers in Palestine and for nurses and clinical officers in Kenya demonstrate that the guide is intended to be feasible and effective when used by non-specialists, including nurses, in routine community and primary care practice . The guide’s criteria are deliberately conservative: they avoid over-treating isolated or same-day seizure clusters while still ensuring structured follow-up. The
3-month review interval allows the nurse to monitor whether additional seizures occur, which would then satisfy the mhGAP-IG threshold and prompt initiation of maintenance antiepileptic medicine.
The child’s developmental delays—difficulty dressing himself and reading simple words at age 9, with a history of reaching milestones later than siblings—are noted in the scenario. These features suggest a possible underlying neurodevelopmental condition, but they do not change the mhGAP-IG epilepsy algorithm. The mhGAP-IG child and adolescent mental and behavioural disorders module addresses developmental concerns separately, and adaptation of that module for local contexts has been studied in Kenya . In this scenario, the developmental history is contextual information; the epilepsy decision is driven solely by the seizure timing criteria.
| Seizure episode | Timing | Within past 12 months? | Counts as a “different day” event? |
|---|
| Episode 1 | 14 months ago | No | No (outside window) |
| Episode 2 | 2 weeks ago, morning | Yes | Yes (day 1) |
| Episode 3 | 2 weeks ago, afternoon | Yes | No (same day as episode 2) |
The mhGAP-IG threshold of two seizures on two different days within one year is not met, so maintenance antiepileptic medicine is not started at this visit. Urgent referral is not indicated because the episodes are not status epilepticus, are not increasing in frequency across separate days, and the child is currently stable. An electroencephalogram is not required before initiating treatment under mhGAP-IG; the guide supports clinical diagnosis based on seizure history when criteria are met, which is especially relevant in settings where EEG access is limited . The nurse’s plan of weekly home visits over the next
2 months is consistent with close monitoring, and the formal reassessment at
3 months provides the structured follow-up point specified by the mhGAP-IG algorithm.