Prioritize assessment using the ABC framework. In suspected anaphylaxis, immediately assess for respiratory compromise such as bilateral wheezing or stridor, which indicate bronchoconstriction and airway edema.
A respiratory rate of 28 breaths per minute in a 16-year-old is tachypnea, a critical sign of distress. Local findings like swelling (3 cm area) or pain (6/10) do not indicate systemic involvement.
Do not wait for hypotension to diagnose anaphylaxis. Respiratory symptoms and gastrointestinal involvement are often the earliest and most dangerous signs in children.
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