A WBC count of 2,000/mm³ indicates severe immunosuppression. The priority is strict infection control to prevent sepsis, the most life-threatening complication.
Implement protective isolation with strict hand hygiene. Monitor for subtle signs of infection, as the typical inflammatory response (redness, pus) may be absent. A fever of 38.0°C (100.4°F) or higher is a medical emergency.
Avoid rectal temperatures, suppositories, and enemas to prevent mucosal tears. No fresh flowers or raw foods. Immediate antibiotic administration is critical once cultures are drawn.
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