A 3-year-old child is admitted to the pediatric oncology uni… | 마이메르시 MyMerci
Child Health
문제
A 3-year-old child is admitted to the pediatric oncology unit with a suspected neuroblastoma. Which assessment finding would be most characteristic of this condition?
The nurse is conducting an initial assessment of a toddler with suspected neuroblastoma.
1Petechiae and bruising on the extremities
2Enlarged lymph nodes in the neck and axilla
3Firm, non-tender abdominal mass with hypertension✓ 정답
4Bone pain and pathological fractures
해설
Neuroblastoma commonly presents as an abdominal mass, often accompanied by hypertension due to catecholamine release from the tumor.
심화 해설
Core Nursing ExplanationKey Concept Analysis: This question assesses your knowledge of the classic presentation of neuroblastoma, the most common extracranial solid tumor in childhood. Neuroblastoma arises from primitive neural crest cells, which develop into the sympathetic nervous system and adrenal medulla. The most common primary site is the abdomen (about 65%), specifically from the adrenal gland or sympathetic ganglia along the spine. The tumor's pathophysiology directly explains its characteristic findings: a mass effect from the primary tumor and the secretion of catecholamines (like epinephrine and norepinephrine).
Answer Rationale: Key Point! The correct answer is a firm, non-tender abdominal mass with hypertension. This combination is highly characteristic. The abdominal mass is often discovered incidentally during bathing or a routine check-up. The hypertension results from the tumor secreting catecholamines, which cause vasoconstriction and increase cardiac output. It is a paraneoplastic syndrome specific to tumors of neural crest origin like neuroblastoma and pheochromocytoma.
Distractor Analysis:
Watch out for confusion!Option ① (Petechiae and bruising): These are signs of bone marrow suppression (thrombocytopenia) and are classic presenting features of leukemia, not the primary finding for a solid tumor like neuroblastoma.
Watch out for confusion!Option ② (Enlarged lymph nodes): While neuroblastoma can metastasize to lymph nodes, generalized or prominent lymphadenopathy is more characteristic of lymphoma or, again, leukemia.
Watch out for confusion!Option ④ (Bone pain and pathological fractures): This is a very important finding in advanced neuroblastoma, as it commonly metastasizes to the bone and bone marrow. However, the question asks for the most characteristic finding, which points to the primary tumor presentation. Bone pain indicates metastatic disease, not the initial, most characteristic local finding.
Related Concepts: Other potential signs of neuroblastoma include "raccoon eyes" (periorbital ecchymosis from orbital metastasis), opsoclonus-myoclonus syndrome (a paraneoplastic neurological disorder), and Horner's syndrome (if the tumor is in the cervical sympathetic chain). Diagnosis involves urine tests for catecholamine metabolites (VMA, HVA), imaging (CT, MRI, MIBG scan), and bone marrow biopsy.
Concept Summary
Neuroblastoma: A malignant tumor of the sympathetic nervous system.
Most Common Site: Abdomen (Adrenal gland or paravertebral ganglia).
Classic Triad (not always all present): 1) Abdominal mass, 2) Hypertension, 3) Increased urinary catecholamines (VMA/HVA).
Common Metastasis Sites: Bone, bone marrow, liver, skin.
Side-by-Side Comparison!
Feature
Neuroblastoma (Solid Tumor)
Acute Lymphoblastic Leukemia (ALL - Liquid Tumor)
Typical Age
Infants, toddlers (
임상 시나리오
Nursing Clinical Practice GuideClinical Scenario: You are the nurse on the pediatric oncology unit. A 3-year-old named Leo is admitted for workup of a large, firm mass palpated in his right upper quadrant during a well-child visit. His mother says he's been more irritable and sweating a lot. His initial BP is 128/84 mmHg (normal for age ~ 90-110/55-70).
Nursing Intervention Strategy:
1. Assessment: Perform a thorough abdominal assessment. Inspect for distension or visible mass. Palpate gently for location, size, mobility, and tenderness (usually non-tender). Auscultate for bowel sounds before palpation. Monitor vital signs closely, especially BP. Assess for signs of metastasis: bone pain, limping, periorbital swelling/ecchymosis ("raccoon eyes"), proptosis (bulging eyes).
2. Diagnostic Support: Collect 24-hour urine for VMA and HVA (catecholamine metabolites). Ensure proper collection technique (acidified container, keep on ice). Prepare the child and family for imaging (ultrasound, CT/MRI) and possibly a bone marrow aspiration/biopsy.
3. Managing Hypertension: Administer prescribed antihypertensives. Provide a calm, low-stimulus environment to help lower BP. Educate parents on signs of hypertensive crisis (severe headache, vomiting, vision changes).
4. Pre-operative Care: If surgery is planned, meticulous BP control is essential. The tumor is very vascular, and manipulating it can cause a catecholamine surge.
Patient Safety and Precautions:
* Key Point!Do NOT vigorously palpate the abdominal mass. Excessive manipulation can cause the release of catecholamines, potentially triggering a hypertensive crisis.
* Handle the child gently. Bone metastases can make them prone to pathological fractures.
* During chemotherapy, monitor for side effects like myelosuppression (neutropenia, anemia, thrombocytopenia), mucositis, and nausea/vomiting.
Nursing Procedure & Medication Flow24-Hour Urine Collection for VMA/HVA:
1. Discard the first morning void. Note the time.
2. Collect ALL urine for the next 24 hours in a special container with preservative (usually hydrochloric acid - CAUTION: corrosive).
3. Keep the collection container on ice or refrigerated.
4. At the end of 24 hours, void one final time and add it to the container.
5. Label accurately and send to lab promptly.
Antihypertensive Administration: For alpha-blockers like phenoxybenzamine, monitor for first-dose orthostatic hypotension. Teach parents to have the child rise slowly. Monitor heart rate with beta-blocker use.
A Word from Your Senior Nurse
"Neuroblastoma is a tough diagnosis, but nurses play a pivotal role from detection through treatment. That firm abdominal mass you might feel during an assessment is your first clue. Remember, your gentle touch isn't just about comfort—it's a safety measure to prevent a catecholamine spike. When you see hypertension in a toddler, think beyond primary hypertension; think 'tumor' until proven otherwise. Connecting these dots—the mass, the high BP, the toddler's age—is the kind of critical thinking that saves lives and will definitely show up on your NCLEX. You've got this!"
핵심 개념
Neuroblastoma — A malignant tumor arising from neural crest cells of the sympathetic nervous system, most common in early childhood. Often presents as an abdominal mass and may secrete catecholamines.
Catecholamines — Hormones (e.g., epinephrine, norepinephrine, dopamine) produced by the adrenal medulla and sympathetic nerves. Secretion by neuroblastoma tumors can cause paraneoplastic syndromes like hypertension.
Vanillylmandelic Acid — A metabolite of catecholamines (epinephrine/norepinephrine). Elevated urinary VMA is a key diagnostic marker for neuroblastoma and pheochromocytoma.
Paraneoplastic Syndrome — A set of signs and symptoms caused by a cancer that are not due to the local presence of tumor cells but by substances (like hormones) secreted by the tumor. Hypertension in neuroblastoma is an example.
Pathological Fracture — A bone fracture that occurs due to weakness of the bone structure from an underlying disease process (e.g., cancer metastasis, osteoporosis), not from significant trauma. A sign of bone metastasis in neuroblastoma.
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