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학습 자료 둘러보기 →In an HIV-exposed newborn, temperature instability (fever or hypothermia) combined with behavioral changes like irritability are cardinal signs of neonatal sepsis. This requires immediate intervention per the Surviving Sepsis Campaign guidelines.
A positive HIV DNA PCR test at 24 hours confirms in utero transmission and is critical, but the clinical signs of active infection take priority for immediate action. Expected findings include maternal HIV antibodies in the infant's blood and a weight loss of up to 7-10% in the first 48 hours.
A compromised immune system in an HIV-exposed infant increases vulnerability to pathogens. Do not delay a full septic workup and initiation of broad-spectrum antibiotics when clinical signs are present, even while awaiting virologic test results.
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