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학습 자료 둘러보기 →The recovery phase in nephrotic syndrome creates a profoundly immunocompromised state. The disease causes urinary loss of immunoglobulins, while corticosteroid therapy suppresses cellular immunity. This dual effect makes the patient exceptionally vulnerable to fulminant, opportunistic infections that can rapidly progress to sepsis.
Prioritize strict infection control measures: enforce meticulous hand hygiene for all contacts, implement protective isolation if indicated, and ensure all equipment is dedicated or thoroughly disinfected. Monitor closely for subtle signs of infection, such as a low-grade fever, as the inflammatory response may be blunted.
A low-grade temperature in this population is a critical finding. Do not dismiss it; it may be the only early sign of a life-threatening infection. Avoid rectal temperatures or suppositories due to the risk of mucosal injury and bacterial entry. Live vaccines are contraindicated during high-dose steroid therapy.
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