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학습 자료 둘러보기 →The MMR vaccine is a live attenuated vaccine. In an immunocompromised patient, the weakened virus can replicate uncontrollably, causing severe infection.
High-dose corticosteroid therapy (e.g., for severe asthma) induces significant immunosuppression. This is a major contraindication for all live vaccines.
Hold live vaccines in patients receiving high-dose systemic corticosteroids (typically >2 mg/kg/day or >20 mg/day of prednisone for >14 days). Vaccination should be deferred for at least 1 month after therapy discontinuation.
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