Certain infectious and parasitic diseases
문제
Patient requires ______ therapy for refractory septic shock.
New Amsterdam Season 2 Episode 11
-
1
vasopressor
✓ 정답
-
2
inotropic
-
3
antiarrhythmic
-
4
anticoagulant
-
5
fibrinolytic
해설
Vasopressor' support is essential in treating hypotension unresponsive to fluid resuscitation in septic shock.
임상 시나리오
Septic Shock Treatment Guidelines:
1. First-line vasopressors:
- Norepinephrine (first choice)
- Epinephrine (alternative)
- Vasopressin (adjunct)
2. Clinical indicators:
- MAP < 65 mmHg
- Serum lactate > 2 mmol/L
- Signs of organ dysfunction
3. Treatment sequence:
- Initial fluid resuscitation
- Vasopressor initiation
- Source control
- Broad-spectrum antibiotics
4. Hemodynamic targets:
- MAP ≥ 65 mmHg
- Urine output > 0.5 mL/kg/hr
- Improved tissue perfusion
5. Monitoring parameters:
- Continuous BP monitoring
- Central venous pressure
- ScvO2
- Lactate clearance
6. Additional interventions:
- Mechanical ventilation if needed
- Glycemic control
- Stress ulcer prophylaxis
- DVT prophylaxis
핵심 개념
- vasopressor — Medications that cause vasoconstriction, increasing blood pressure by tightening blood vessels
- inotropic — Drugs that alter the force of heart muscle contraction, affecting cardiac output
- antiarrhythmic — Medications used to treat and prevent irregular heartbeats or cardiac arrhythmias
- anticoagulant — Medications that prevent blood clot formation by interfering with the blood coagulation process
- fibrinolytic — Drugs that break down blood clots by activating plasminogen to dissolve fibrin
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