Quick answerAcute hemolytic transfusion reaction; stop the transfusion and keep the bag, infuse normal saline through new tubing, and monitor hourly urine output and color along with blood pressure and heart rate.
Why this is correctFever alone could be a febrile nonhemolytic reaction, but this client also has back pain, hypotension, and dark urine, which signal intravascular hemolysis. New tubing avoids giving more of the incompatible blood still in the line, and saline supports blood pressure and urine flow to protect the kidneys from free hemoglobin.
Easy analogy or mental picturePicture the wrong key forced into a lock: the red cells burst open, and the debris (hemoglobin) clogs the kidneys, darkening the urine.
Memory hookFever + back pain + dark urine in the first minutes = hemolysis: stop, save, saline, new line.
NCLEX decision ruleFor any suspected transfusion reaction, stop the product first; then use the accompanying signs to name the type and choose what to monitor.
Why the other choices are wrongA febrile nonhemolytic reaction causes fever and chills without hypotension or hemoglobinuria, so acetaminophen and resuming the unit are unsafe here. Anaphylaxis would bring hives, wheezing, or angioedema, and it does not cause fever or dark urine, so epinephrine and urticaria checks do not fit. Circulatory overload causes hypertension, crackles, and distended neck veins, so BNP is not the right marker. Slowing the rate continues exposure to incompatible blood. Temperature every 4 hours is too infrequent and nonspecific.
References
1MedlinePlus — Hemolytic transfusion reactionSymptoms include fever, chills, back pain, and dark urine; the transfusion must be stopped.
2CDC NHSN — Hemovigilance Module ProtocolDefines acute hemolytic, febrile nonhemolytic, allergic, and TACO reaction criteria.