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Pathophysiology

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The child has had fever for 6 days despite oral amoxicillin, with bilateral red eyes without discharge, cracked lips and a strawberry tongue, a polymorphous truncal rash, red and swollen hands and feet, and a 1.8-cm unilateral cervical lymph node. There is no vomiting, diarrhea, or known COVID-19 exposure, and the rapid strep test is negative. This presentation meets criteria for . With BP 92/54 mm Hg, clear lungs, and SpO2 98% on room air, the complication of greatest concern is , which the nurse anticipates will first be evaluated with . Because the fever began 6 days ago, IVIG should be given .
The child has had fever for 6 days despite oral amoxicillin, with bilateral red eyes without discharge, cracked lips and a strawberry tongue, a polymorphous truncal rash, red and swollen hands and feet, and a 1.8-cm unilateral cervical lymph node. There is no vomiting, diarrhea, or known COVID-19 exposure, and the rapid strep test is negative. This presentation meets criteria for . With BP 92/54 mm Hg, clear lungs, and SpO2 98% on room air, the complication of greatest concern is , which the nurse anticipates will first be evaluated with . Because the fever began 6 days ago, IVIG should be given .
Explanation
Fever for at least 5 days with all five principal features (including a node of at least 1.5 cm) meets criteria for classic, not incomplete, Kawasaki disease, and the absence of GI symptoms, shock, and COVID-19 exposure argues against MIS-C. Normal BP, clear lungs, and normal oxygenation make heart failure or tamponade unlikely, so coronary aneurysm is the key threat; transthoracic echocardiography is the first-line noninvasive coronary study in children, and IVIG is given now, within 10 days of fever onset, without waiting for an abnormal echocardiogram.
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