A 24-year-old client weighing 60 kg presents 6.5 hours after… | MyMerci
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Adverse Effects/Contraindications/Interactions

A 24-year-old client weighing 60 kg presents 6.5 hours after ingesting 15 g (250 mg/kg) of immediate-release acetaminophen. The 4-hour concentration is 185 mcg/mL, baseline AST and ALT are normal, and the initial acetylcysteine loading order was written as 6,000 mg instead of 9,000 mg. Which actions belong in the immediate overdose plan? Select exactly 4 responses.

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Choose your responses, then check the answer.

Select exactly 4 responses.
Explanation
Verify the ingestion history, contact poison-center or toxicology support, begin the corrected weight-based acetylcysteine regimen promptly, and trend the acetaminophen concentration and hepatic, coagulation, renal, glucose, and electrolyte measures. Delaying treatment for another level is unsafe because the known 4-hour concentration of 185 mcg/mL is above the treatment line even with normal initial aminotransferases. The 60-kg client requires the full 150-mg/kg loading dose of 9,000 mg; giving 6,000 mg and waiting for symptoms or liver injury before completing it is not an acceptable loading strategy.
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