Quick answerThe correct order is: activate stroke pathway and confirm last known well; perform rapid neurologic assessment and stabilize ABCs; obtain urgent brain imaging; determine reperfusion eligibility; maintain NPO and monitor.
Why this is correctStroke care is time-critical. The first step is to activate the stroke team and establish the exact time of symptom onset, which determines eligibility for thrombolysis. Immediate assessment of airway, breathing, circulation, and neurologic status is essential but should not delay activation. Brain imaging is required to distinguish ischemic from hemorrhagic stroke before reperfusion decisions. Reperfusion eligibility can only be determined after imaging and review of contraindications. Ongoing monitoring and NPO status are important but are lower priority than acute treatment decisions.
Clinical pictureIn acute stroke, the goal is to minimize time to treatment. The AHA/ASA guidelines emphasize rapid activation, assessment, imaging, and treatment. Blood glucose must be checked early to rule out hypoglycemia as a mimic, but this is part of the initial assessment. Warfarin use and elevated INR are contraindications to thrombolysis, so coagulation status must be considered before reperfusion.
Memory hookRemember the stroke chain of survival: Detection, Dispatch, Delivery, Door, Data, Decision, Drug, Disposition. The nursing actions align with Door-to-Data and Data-to-Decision steps.
NCLEX decision rulePrioritize actions that are time-sensitive and prerequisite to others. Activation and last known well time precede assessment details because they mobilize resources and establish eligibility. Imaging precedes reperfusion decisions. Monitoring and NPO are supportive and follow acute treatment.
Why the alternatives are wrongIf the client had hypoglycemia, glucose correction would be first. If the client had airway compromise, ABC stabilization would precede pathway activation. If imaging showed hemorrhage, reperfusion would be contraindicated and blood pressure management would take priority.
Sources
1NCSBN 2026 NCLEX-RN Test Plan
2AHA/ASA 2026 Acute Ischemic Stroke Guideline: Top Things to Know
3NCSBN 2026 NCLEX-RN Test Plan