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Laboratory Values

An adult with DKA is being treated with IV fluids, insulin drip, and electrolyte replacement. Review the recovery trend across 6 hours and answer the questions.

Trend

Choose your responses, then check the answer.

TimeData
0 hoursglucose: 450 mg/dL; anion gap: 22 mEq/L; pH: 7.22; bicarbonate: 12 mEq/L; potassium: 5.2 mEq/L
2 hoursglucose: 380 mg/dL; anion gap: 19 mEq/L; pH: 7.26; bicarbonate: 14 mEq/L; potassium: 4.8 mEq/L
4 hoursglucose: 290 mg/dL; anion gap: 16 mEq/L; pH: 7.30; bicarbonate: 16 mEq/L; potassium: 4.2 mEq/L
6 hoursglucose: 210 mg/dL; anion gap: 14 mEq/L; pH: 7.33; bicarbonate: 17 mEq/L; potassium: 4.0 mEq/L

Q1. Which interpretation of the 6-hour trend is most accurate?

Q2. At 6 hours, the glucose is 210 mg/dL and the anion gap is 14 mEq/L. What is the priority action?

Q3. Which parameter is the best indicator that the insulin drip can be safely discontinued?

Explanation
The trend shows steady DKA resolution: glucose falling, anion gap closing, pH and bicarbonate normalizing, potassium maintained with replacement. The priority action when GLUCOSE reaches 200-250 is to ADD DEXTROSE to the IV fluids while CONTINUING THE INSULIN DRIP to keep clearing ketones and closing the anion gap. Stopping insulin too early (before AG closes) reopens the acidosis. Potassium replacement continues with insulin until DKA is resolved.
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