Clinical context A 29-year-old with recurrent vulvovaginal c… | MyMerci
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Adverse Effects/Contraindications/Interactions

Clinical context A 29-year-old with recurrent vulvovaginal candidiasis is scheduled for another ibrexafungerp course; the nurse reviews pregnancy status, newly added medicines, interaction management, and administration plans. Highlight the medication-reconciliation findings that require clarification before the next ibrexafungerp dose.

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DomainFinding
Pregnancy status Pregnancy test is positive before the scheduled dose
Pregnancy status Pregnancy test is negative before the scheduled dose.
Medication list Rifampin was started for another condition
Medication list Itraconazole was added and the ibrexafungerp dose was reduced to 150 mg twice daily.
Medication list Itraconazole was added but no ibrexafungerp dose review is documented
Administration The tablets will be swallowed with water
Education The client keeps an updated medication list
Assessment Temperature is normal and the client denies rash
Explanation
Pregnancy is a contraindication. A strong CYP3A inhibitor requires a labeled dose modification, while a strong or moderate CYP3A inducer should be avoided because it can reduce ibrexafungerp exposure.
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