A client started fezolinetant for menopausal vasomotor symptoms 3 weeks ago. The client now reports fatigue, pruritus, dark urine, and right-upper-quadrant pain. Which action should the nurse take?

1 Tell the client to stop fezolinetant now and obtain prompt medical evaluation with hepatic laboratory testing. ✓ Correct answer
2 Recommend taking the next dose with a high-fat meal.
3 Reassure the client that these findings indicate effective symptom control.
4 Delay reporting the symptoms until the routine 9-month laboratory visit.

Explanation

Fatigue, pruritus, dark urine, and right-upper-quadrant pain can signal fezolinetant-associated liver injury. The label directs immediate discontinuation and medical evaluation with hepatic testing when these symptoms occur.

Next question on this topicA nurse is reviewing the morning lab results for an adult client receiving warfarin for at…

In-depth explanation

Quick answer
Stop fezolinetant and escalate new symptoms of liver injury immediately.

Why this is correct
Fezolinetant has a boxed warning for hepatotoxicity and requires baseline and scheduled liver testing. Symptom-triggered action is immediate and does not wait for the next routine monitoring point.

Easy analogy or mental picture
Build a medication-safety chain: identify the new cue, connect it to the drug mechanism or labeled limitation, stop preventable exposure, stabilize the client, and verify a measurable response.

Memory hook
Drug, urgent cue, protective action, and reassessment endpoint.

NCLEX decision rule
Choose the action that prevents the most immediate medication-related harm while preserving indicated treatment and required monitoring.

Why the other choices are wrong
Options that continue a suspect exposure, normalize a labeled danger cue, substitute an unauthorized dose, or delay escalation leave the client at risk.

References

1DailyMed: VEOZAH (fezolinetant)Boxed hepatotoxicity warning, scheduled hepatic laboratory monitoring, symptom-triggered discontinuation, and CYP1A2 inhibitor contraindication

Clinical scenario

Medication-safety review
Verify indication, current assessment, dose and route, organ function, interactions, urgent toxicity cues, authorized action, and measurable follow-up.

Browse all questions No login required

Master the NCLEX-RN with MyMerci

Thousands of NCLEX-style questions with detailed rationale — in your language. Track your progress and study smarter.

Start for free

App Store Google Play

Read in another language: English 한국어 日本語繁體中文 Tiếng Việt

For study reference only. Always follow current clinical guidelines and your institution’s protocols.

성장을 멈추지 마세요

A client started fezolinetant for menopausal vasomotor symptoms 3 weeks ago. The client now reports fatigue, pruritus, dark urine, and right-upper-quadrant pain. Which action should the nurse take?

In-depth explanation

Clinical scenario

Master the NCLEX-RN with MyMerci