A client taking nintedanib for progressive fibrosing lung di… | MyMerci
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Adverse Effects/Contraindications/Interactions

A client taking nintedanib for progressive fibrosing lung disease develops new findings. Which action should the nurse take first?

Chart/Exhibit

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History
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Labs
Orders
Notes
Progressive fibrosing interstitial lung disease treated with nintedanib
BP 92/56 mm Hg, HR 114/min, respirations 22/min
ALT 286 units/L, AST 241 units/L, total bilirubin 3.1 mg/dL, creatinine 1.5 mg/dL from 0.9 mg/dL
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Explanation
Persistent diarrhea with poor intake plus jaundice, dark urine, and markedly elevated liver tests suggests serious nintedanib toxicity requiring interruption and urgent evaluation.
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