Review the daptomycin treatment trend and determine the priority interpretation and action.
Trend
Choose your responses, then check the answer.
Explanation
New proximal muscle pain and weakness with a marked CPK increase during daptomycin therapy suggests myopathy; hold the dose and obtain prompt prescriber and pharmacist evaluation while reviewing renal function and concurrent statin use.
Quick answer The trend supports daptomycin-associated muscle toxicity.
Why this is correct The label directs CPK and symptom monitoring, with more frequent assessment in renal impairment or concurrent HMG-CoA reductase inhibitor use. New weakness and a substantial CPK rise require immediate review.
Easy analogy or mental picture The muscle warning light and laboratory gauge are rising together.
Memory hook Daptomycin plus weakness plus rising CPK: hold and review.