A central venous access device remains occluded 30 minutes after the prescribed Cathflo Activase dose was instilled. Which action is appropriate?

• 1 Forcefully flush the lumen with 20 mL saline, then reconnect the infusion without checking blood return.
• 2 Administer a third 2 mg alteplase dose immediately because the first treatment has failed at 30 minutes.
• 3 Remove the catheter immediately and insert a new device without completing the prescribed dwell assessment.
• 4 Allow the prescribed dose to dwell, reassess catheter function at 120 minutes, and then consider a second dose if needed. ✓ Correct answer

For study reference only. Always follow current clinical guidelines and your institution’s protocols.