A client develops wheezing, generalized hives, and blood pressure 78/42 mm Hg after receiving an antibiotic. Which medication should the nurse prepare to administer first?
1Intramuscular epinephrine✓ Correct answer
2Inhaled corticosteroid
3Oral diphenhydramine
4Oral acetaminophen
Explanation
Wheezing, hives, and hypotension after antibiotic exposure indicate anaphylaxis. Intramuscular epinephrine is the first-line medication because it supports airway, breathing, and circulation. Antihistamines or corticosteroids may be adjuncts but do not replace epinephrine for life-threatening anaphylaxis.