Ten minutes into a PRBC transfusion, a client develops chill… | MyMerci
Adverse Effects/Contraindications/Interactions PPT
Question

Ten minutes into a PRBC transfusion, a client develops chills, fever, severe back pain, dyspnea, and red urine. Which is the priority sequence of actions?

Explanation
Correct (2): Classic acute hemolytic transfusion reaction (ABO incompatibility) — chills, fever, flank/back pain, hypotension, hemoglobinuria, dyspnea, DIC, AKI. STOP transfusion, DISCONNECT TUBING (do not just clamp), maintain IV with NS via NEW tubing, notify, send unit + new blood/urine specimens for workup, supportive care. (1,3,4) Continue to expose client to fatal antigen.

In-depth explanation

Memory Tip Acute hemolytic = "Fever + Flank pain + Red urine + Shock" within 15 min. STOP-DISCONNECT-SALINE-NOTIFY-SEND. Differentiate from febrile non-hemolytic (fever only, no hemolysis signs).

Clinical scenario

Scenario 50-year-old female 10 min into PRBC transfusion; new chills, fever 38.6°C, severe back pain, dyspnea, red urine, BP dropping.

Key concepts

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For study reference only. Always follow current clinical guidelines and your institution’s protocols.