Correct (2): Classic acute hemolytic transfusion reaction (ABO incompatibility) — chills, fever, flank/back pain, hypotension, hemoglobinuria, dyspnea, DIC, AKI. STOP transfusion, DISCONNECT TUBING (do not just clamp), maintain IV with NS via NEW tubing, notify, send unit + new blood/urine specimens for workup, supportive care. (1,3,4) Continue to expose client to fatal antigen.
Clinical scenario
Scenario 50-year-old female 10 min into PRBC transfusion; new chills, fever 38.6°C, severe back pain, dyspnea, red urine, BP dropping.
For study reference only. Always follow current clinical guidelines and your institution’s protocols.