A nurse is preparing to administer 1 unit of PRBCs. Which se… | MyMerci
Adverse Effects/Contraindications/Interactions PPT
Question

A nurse is preparing to administer 1 unit of PRBCs. Which set of pre-administration practices is essential to prevent a fatal hemolytic reaction?

Explanation
Correct (2): Two-RN bedside verification required to prevent ABO incompatibility. Match: client two identifiers, blood product ABO/Rh, unit number, expiration, crossmatch results. Use NS ONLY (D5W causes hemolysis; LR contains Ca that clots). Start slowly, stay with client first 15 min — most severe reactions occur within 15 min. Each unit must be completed within 4 hours. (1,3,4) Dangerous.

In-depth explanation

Memory Tip Transfusion 4 rules = "2-RN check, NS only, Start slow + watch 15 min, 4-hr max." Vitals pre, 15 min, 1 hr, end. Stop and assess for any reaction.

Clinical scenario

Scenario Adult with symptomatic anemia ordered for 1 unit PRBCs. Unit retrieved from blood bank.

Key concepts

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For study reference only. Always follow current clinical guidelines and your institution’s protocols.