A critically ill client on prolonged propofol infusion develops metabolic acidosis, rhabdomyolysis, hyperkalem…

Question

A critically ill client on prolonged propofol infusion develops metabolic acidosis, rhabdomyolysis, hyperkalemia, and arrhythmias. Which is the nurse's priority interpretation?

Accepted Answer

Option 3: Propofol infusion syndrome (PRIS) — stop the infusion, switch to alternative sedation (midazolam/dexmedetomidine), supportive care including hemodialysis if needed

Correct (2): Propofol infusion syndrome (PRIS) — rare but fatal complication of prolonged high-dose propofol (>48 hours, >4 mg/kg/hr). Mitochondrial dysfunction → metabolic acidosis, rhabdomyolysis, hyperkalemia, AKI, cardiac failure. STOP propofol, switch sedation (midazolam, dexmedetomidine), supportive care (renal replacement, vasopressors). Also screen for egg/soy allergy before starting propofol. (1,3,4) Worsen.

Answer

Option 1: Expected drug effect

Answer

Option 2: Increase propofol for better sedation

Answer

Option 4: Add albuterol for hyperkalemia only

A critically ill client on prolonged propofol infusion develops metabolic acidosis, rhabdomyolysis, hyperkalemia, and arrhythmias. Which is the nurse's priority interpretation?

In-depth explanation

Clinical scenario

Key concepts

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A critically ill client on prolonged propofol infusion develops metabolic acidosis, rhabdomyolysis, hyperkalemia, and arrhythmias. Which is the nurse's priority interpretation?

In-depth explanation

Clinical scenario

Key concepts

Master the NCLEX-RN with MyMerci