A client on bevacizumab for metastatic colon cancer reports … | MyMerci
Medical Emergencies PA
Question

A client on bevacizumab for metastatic colon cancer reports severe abdominal pain and bloody diarrhea. Which is the nurse's priority interpretation?

Explanation
Correct (2): Bevacizumab (anti-VEGF) impairs wound healing; boxed warnings: GI perforation, severe bleeding, thrombosis, hypertension, proteinuria, wound dehiscence. Severe abdominal pain + bloody diarrhea raises concern for perforation — urgent. (1,3) Wrong scope. (4) Treatment plan, not acute action.

In-depth explanation

Memory Tip Bevacizumab = "Block VEGF = Block Vessels = Bleed/Block." Watch HTN, proteinuria, GI perf, wound dehiscence. Hold 4-6 weeks around surgery.

Clinical scenario

Scenario 60-year-old male on bevacizumab 8 weeks; new severe abdominal pain, bloody diarrhea, BP 168/98.

Key concepts

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For study reference only. Always follow current clinical guidelines and your institution’s protocols.