Correct (2): Tumor lysis syndrome = massive cell breakdown → hyperkalemia, hyperphosphatemia, hyperuricemia, hypocalcemia, AKI. Prophylaxis: aggressive hydration + allopurinol (xanthine oxidase inhibitor); rasburicase (recombinant urate oxidase) for high risk or established TLS — converts uric acid to allantoin. Avoid in G6PD deficiency (hemolysis risk). (1,3,4) Unrelated.
In-depth explanation
Memory Tip TLS = "Tumor Lyse Syndrome" — K↑, P↑, Uric acid↑, Ca↓. Prophylaxis: HYDRATE + ALLOPURINOL ± RASBURICASE.
For study reference only. Always follow current clinical guidelines and your institution’s protocols.