Correct (2): Sevelamer binds dietary phosphate — must take WITH meals to be effective. Separate other medications (especially ciprofloxacin, levothyroxine, mycophenolate, tacrolimus) by ≥1h before or ≥3h after. Common: constipation, dyspepsia. (1,3) Reduces effectiveness. (4) Scheduled.
In-depth explanation
Memory Tip Phosphate binders = "With meals." Sevelamer (non-calcium, expensive). Calcium acetate (cheap but Ca load). Lanthanum, ferric citrate alternatives.
For study reference only. Always follow current clinical guidelines and your institution’s protocols.