A nurse counsels a client on long-term omeprazole therapy ab… | MyMerci
Medical Emergencies PA
Question

A nurse counsels a client on long-term omeprazole therapy about adverse effects with prolonged use. Which group of risks should the nurse emphasize?

Explanation
Correct (2): Long-term PPI use (>1 year) is associated with hypomagnesemia, B12 deficiency, increased C. difficile infection, community-acquired pneumonia, osteoporotic fractures (hip/spine), interstitial nephritis, and CKD. Use the lowest effective dose and consider de-escalation when indication resolves. (1,3,4) Wrong direction.

In-depth explanation

Memory Tip Long-term PPI = "M.B.C. (Magnesium·B12·C.diff·CKD)·Fractures·Pneumonia." Yearly Mg, B12 check; reassess indication annually.

Clinical scenario

Scenario 62-year-old female on omeprazole 20 mg PO daily × 5 years for GERD. Provider requests counseling about long-term PPI risks.

Key concepts

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For study reference only. Always follow current clinical guidelines and your institution’s protocols.