Parents of a 10-year-old child on levetiracetam for new-onse… | MyMerci
Crisis Intervention PSI
Question

Parents of a 10-year-old child on levetiracetam for new-onset epilepsy report new irritability, aggression, and emotional outbursts since starting therapy. Which is the nurse's best response?

Explanation
Correct (2): Behavioral adverse effects — irritability, aggression, mood changes, depression, suicidal ideation — are well-documented levetiracetam side effects, especially in children and adolescents. Some clinicians add pyridoxine (B6) which may attenuate symptoms; otherwise switching agents. (1) Dismisses a known adverse effect. (3) Higher dose worsens behavior. (4) Abrupt discontinuation risks seizure rebound.

In-depth explanation

Memory Tip Levetiracetam = "Lev-er-RAGE-tam" — irritability and rage. CPG Screen for mood/behavior at every follow-up; suicide risk warning class-wide for anticonvulsants.

Clinical scenario

Scenario 10-year-old boy started levetiracetam 250 mg PO BID 3 weeks ago for new generalized epilepsy. Parents report new irritability, aggression, and outbursts at school. Seizures controlled.

Key concepts

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