The nurse prepares prescribed IV lorazepam for an adult with… | MyMerci
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Adverse Effects/Contraindications/Interactions PPT
Question

The nurse prepares prescribed IV lorazepam for an adult with status epilepticus. Which administration action is appropriate?

Explanation
For adult status epilepticus, IV lorazepam is administered slowly at a rate no faster than 2 mg/min after product-specific dilution. Respiratory depression is the most important risk, so airway patency, respirations, oxygenation, and vital signs require close monitoring with ventilation equipment available. Rapid IV administration, delaying airway assessment, or mixing lorazepam with an opioid creates avoidable respiratory danger.
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In-depth explanation

Clinical reasoning
Lorazepam can terminate seizure activity but can also depress ventilation and compound postictal impairment of consciousness. Slow administration and airway readiness must occur together.

Decision rule
For IV lorazepam in adult status epilepticus, do not exceed 2 mg/min and maintain continuous respiratory assessment with ventilatory support immediately available.

Clinical scenario

Scenario A 56-year-old male was admitted 48 hours ago for alcohol use disorder withdrawal. CIWA-Ar 28 and a 90-second generalized tonic-clonic seizure just occurred. The provider orders lorazepam 2 mg IV push now. The client has a patent 20-gauge peripheral IV in the left forearm and pulse oximetry of 96% on room air.

Key concepts

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