A client taking lithium for bipolar disorder reports vomitin… | MyMerci
Medical Emergencies PA
Question

A client taking lithium for bipolar disorder reports vomiting and diarrhea for 2 days. The client also started ibuprofen for back pain. The nurse notes coarse hand tremor and unsteady gait. Which action should the nurse take first?

Explanation
Vomiting, diarrhea, dehydration, NSAID use, coarse tremor, and ataxia are red flags for lithium toxicity. NSAIDs can reduce renal lithium clearance. The priority is to hold the medication, notify the prescriber, check lithium level and renal/electrolyte labs, and correct dehydration.

In-depth explanation

Caution Lithium behaves like sodium in the kidney. Dehydration, sodium depletion, NSAIDs, ACE inhibitors, ARBs, and thiazides can increase lithium levels.

Clinical scenario

Scenario Lithium + GI fluid loss + ibuprofen + coarse tremor/ataxia.

Key concepts

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For study reference only. Always follow current clinical guidelines and your institution’s protocols.