A 78-year-old client with coronary artery disease and hypoth… | MyMerci
Adverse Effects/Contraindications/Interactions PA
Question

A 78-year-old client with coronary artery disease and hypothyroidism returns 8 weeks after a levothyroxine increase from 75 to 125 mcg daily. Findings: HR 124 irregular, BP 158/92, palpitations, chest tightness, weight loss 4 kg, tremor, TSH 0.05 mIU/L (below reference), free T4 elevated, ECG atrial fibrillation with rapid ventricular response. Which is the priority nursing action?

Explanation
The picture is iatrogenic thyrotoxicosis from over-replacement: suppressed TSH, elevated free T4, sinus tachycardia or atrial fibrillation with rapid ventricular response, hypertension, weight loss, tremor, and chest tightness. In an older adult with coronary artery disease, excess thyroid hormone increases myocardial oxygen demand and can precipitate angina, AFib with RVR, and heart failure. Priority nursing actions: (1) hold the next dose and notify the prescriber for dose reduction (often by 25 percent) with TSH recheck in 6 weeks, (2) continuous cardiac monitor and 12-lead ECG, (3) assess for chest pain, dyspnea, and signs of ischemia, (4) anticipate beta-blocker for rate control and symptomatic relief, (5) assess fall risk because of tremor and palpitations. Continuing or increasing the dose worsens the imbalance. Atropine accelerates rate and is contraindicated. The geriatric titration rule is start low (12.5 to 25 mcg) and go slow (titrate every 6 to 8 weeks).

In-depth explanation

TSH suppressed plus tachy-AFib in a CAD patient is the classic over-replacement scenario tested on NCLEX. Hold and notify, monitor cardiac status, and prepare for dose reduction with beta-blocker rate control.
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For study reference only. Always follow current clinical guidelines and your institution’s protocols.