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Medication Administration PPT
Question

The nurse provides discharge teaching to a client beginning levothyroxine who also takes a calcium supplement each morning. Which client statement indicates correct understanding?

Explanation
Levothyroxine is taken once daily on an empty stomach, 30 to 60 minutes before breakfast. Calcium can reduce absorption and should be separated by at least 4 hours; therapy and product changes require clinician guidance.
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In-depth explanation

Quick answer
Take levothyroxine before breakfast and 4 hours apart from calcium.

Why this is correct
Food and calcium can reduce levothyroxine absorption. A consistent empty-stomach routine and adequate separation support stable thyroid hormone exposure.

Easy analogy or mental picture
Give levothyroxine an empty lane; calcium can block part of that lane.

Memory hook
30 to 60 before food; 4 hours from calcium.

NCLEX decision rule
For narrow-therapeutic-index replacement therapy, prioritize consistent administration and monitoring rather than symptom-based self-adjustment.

Why the other choices are wrong
Calcium impairs absorption, symptom improvement does not end replacement therapy, and product changes may require reassessment.
References
1DailyMed: Levothyroxine sodiumEmpty-stomach administration and separation from interacting agents
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For study reference only. Always follow current clinical guidelines and your institution’s protocols.