A client with metastatic breast cancer presents with confusion, polyuria, dehydration, and corrected calcium 14.6 mg/dL. Which interventions should the nurse anticipate? Select all that apply.
Select All That Apply
Choose your responses, then check the answer.
Explanation
Severe hypercalcemia of malignancy needs volume expansion FIRST with isotonic saline 200-300 mL/hr targeting urine output 100-150 mL/hr to enhance calciuresis. Calcitonin gives a rapid but tachyphylactic calcium drop within 12-48 hours bridging to bisphosphonate. Zoledronic acid provides sustained reduction over days but is renally cleared — denosumab is preferred if creatinine clearance under 30. Fluid restriction WORSENS hypercalcemia by reducing renal calcium clearance. Loop diuretics are NOT routinely used unless there is fluid overload from rehydration.