Intraoperatively a 25-year-old develops sudden tachycardia, jaw rigidity, ETCO2 doubling, and temperature 40.4 C while under sevoflurane and after succinylcholine. Which interventions should the team implement? Select all that apply.
Select All That Apply
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Explanation
Malignant hyperthermia is a hereditary skeletal muscle channelopathy triggered by volatile anesthetics and succinylcholine. Treatment: STOP triggers, give dantrolene 2.5 mg/kg IV (repeat to 10 mg/kg total), hyperventilate with 100 percent oxygen at high flow to wash out CO2, active cooling (cold saline IV, ice packs, lavage) until temperature 38, treat hyperkalemia and acidosis. Charcoal filters on the anesthesia circuit reduce volatile residual. RESTARTING succinylcholine is contraindicated. Family must be counseled regarding screening.