SVC syndrome from mediastinal mass causes obstruction of venous return with facial/upper-extremity swelling, distended chest-wall collaterals, and dyspnea. Stridor and orthopnea signal airway compromise — elevation of the head of bed reduces venous pressure and facilitates breathing. Emergent oncology and radiation oncology consult is required; treatment is radiation therapy, chemotherapy (especially small cell), or endovascular stenting. Supine positioning WORSENS venous engorgement. Aggressive fluids increase central venous pressure and edema. Compression stockings have no role in SVC obstruction.
For study reference only. Always follow current clinical guidelines and your institution’s protocols.