A 62-year-old client is being discharged 3 days after a succ… | MyMerci
Adverse Effects/Contraindications/Interactions PA
Question

A 62-year-old client is being discharged 3 days after a successful percutaneous coronary intervention with a drug-eluting stent (DES) in the left anterior descending artery. The provider has prescribed aspirin 81 mg daily plus ticagrelor 90 mg twice daily as dual antiplatelet therapy. Which teaching by the nurse is most important?

Explanation
DAPT after DES — duration and procedural management
Dual antiplatelet therapy (aspirin + a P2Y12 inhibitor) is the cornerstone after PCI to prevent stent thrombosis, a catastrophic event with high mortality. Standard durations (subject to bleeding/ischemic risk individualization):
Stable CAD with DES: at least 6 months DAPT, then aspirin lifelong.
ACS (NSTEMI/STEMI) with PCI: at least 12 months DAPT, then aspirin lifelong; longer in high-ischemic risk.
• Bare-metal stent: 1 month minimum (rarely used now).

Premature discontinuation is the strongest predictor of stent thrombosis. Patient teaching:
Never self-stop the P2Y12 inhibitor; notify all providers (PCP, dentist, surgeon, urgent care) before any procedure so timing can be coordinated with cardiology.
• Carry a wallet card with stent type, location, date, and DAPT plan.
• Routine dental cleanings and minor procedures usually do not require holding DAPT.
• Major surgery may require an interruption with bridge plan; ideally elective surgery is delayed until completion of DAPT (≥6-12 months for DES).
Ticagrelor specifics: BID dosing (every 12 hours); aspirin maintenance dose limited to ≤100 mg (higher aspirin reduces ticagrelor benefit); common adverse: dyspnea (~14%), bradyarrhythmia, increased uric acid; do not co-administer with strong CYP3A4 inhibitors.
• Bleeding precautions and immediate reporting (black stool, hemoptysis, severe headache, fall).

In-depth explanation

Clinical reasoning summary
DAPT after DES — duration and procedural management
Dual antiplatelet therapy (aspirin + a P2Y12 inhibitor) is the cornerstone after PCI to prevent stent thrombosis, a catastrophic event with high mortality. Standard durations (subject to bleeding/ischemic risk individualization):
Stable CAD with DES: at least 6 months DAPT, then aspirin lifelong.
ACS (NSTEMI/STEMI) with PCI: at least 12 months DAPT, then aspirin lifelong; longer in high-ischemic risk.
• Bare-metal stent: 1 month minimum (rarely used now).

Premature discontinuation is the strongest predictor of stent thrombosis. Patient teaching:
Never self-stop the P2Y12 inhibitor; notify all providers (PCP, dentist, surgeon, urgent care) before any procedure so timing can be coordinated with cardiology.
• Carry a wallet card with stent type, location, date, and DAPT plan.
• Routine dental cleanings and minor procedures usually do not require holding DAPT.
• Major surgery may require an interruption with bridge plan; ideally elective surgery is delayed until completion of DAPT (≥6-12 months for DES).
Ticagrelor specifics: BID dosing (every 12 hours); aspirin maintenance dose limited to ≤100 mg (higher aspirin reduces ticagrelor benefit); common adverse: dyspnea (~14%), bradyarrhythmia, increased uric acid; do not co-administer with strong CYP3A4 inhibitors.
• Bleeding precautions and immediate reporting (black stool, hemoptysis, severe headache, fall).
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